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PS3 can induce apoptotic death and, in this way, may influence tumor sensitivity to chemotherapeutic agents. ... of ovarian neoplasms, we analyzed the status of the p53 gene in 48 primary ovarian carcinomas obtained from patients subjected to cisplatin-based treatments after surgery. ... Repair -MMR- genes) involved in the DNA repair function When mutated, these genes cause genomic instabilityanbsp;...

Publisher: - 1998

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